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automated peptide synthesizer aapptec apex 396  (AAPPTec Inc)

 
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    Structured Review

    AAPPTec Inc automated peptide synthesizer aapptec apex 396
    Automated Peptide Synthesizer Aapptec Apex 396, supplied by AAPPTec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/apex+396+automated+peptide+synthesizer/apex+396+peptide+synthesizer/us12337042-87-17-19
    Average 90 stars, based on 1 article reviews
    automated peptide synthesizer aapptec apex 396 - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Synthesized:

    Article Title: Discovery of a Potent Conorfamide from Conus episcopatus Using a Novel Zebrafish Larvae Assay.
    Article Snippet: Natural products such as conotoxins have tremendous potential as tools for biomedical research and for the treatment of different human diseases.. Conotoxins are peptides present in the venoms of predatory cone snails that have a rich diversity of pharmacological functions.. One of the major bottlenecks in natural products research is the rapid identification and evaluation of bioactive molecules.

    Article Title: Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus
    Article Snippet: .. The novel peptides described in this study, At1.1 and At1.2 (the analog with an L16I mutation), AtIA[des1Z], and AtIA[des18W], were synthesized using solid-phase Fmoc peptide chemistry with an AAPPTec Apex 396 automated peptide synthesizer (Louisville, KY, USA). ..

    Article Title: Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells
    Article Snippet: .. RgIA-5727 was synthesized on 0.05 mmol scale using an Apex 396 automated peptide synthesizer (AAPPTec, Louisville, KY, United States), applying standard solid-phase Fmoc (9-fluorenylmethyloxycarbonyl) protocols Fmoc-Arg(Pbf)-Wang resin (0.3 mmol/g load; Peptides International). .. All standard amino acids, Fmoc-Pra-OH, Fmoc-Pen(Trt)-OH (Pen), Fmoc-beta-HTyr(tBu)-OH were purchased from AAPPTec except for Fmoc-3-iodo-L-Tyr-OH (I-3-Y) (Peptides International).

    Article Title: Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads
    Article Snippet: .. Consomatin Ro1 was synthesized using an Apex 396 automated peptide synthesizer (AAPPTec, Louisville, KY) applying standard solid-phase Fmoc (9-fluorenylmethyloxy-carbonyl) protocols. .. Peptide was constructed on preloaded Fmoc-Ala-Wang resin (substitution: 0.38 mmol/g; Peptides International, Louisville, KY).

    Construct:

    Article Title: Discovery of a Potent Conorfamide from Conus episcopatus Using a Novel Zebrafish Larvae Assay.
    Article Snippet: Natural products such as conotoxins have tremendous potential as tools for biomedical research and for the treatment of different human diseases.. Conotoxins are peptides present in the venoms of predatory cone snails that have a rich diversity of pharmacological functions.. One of the major bottlenecks in natural products research is the rapid identification and evaluation of bioactive molecules.

    Mutagenesis:

    Article Title: Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus
    Article Snippet: .. The novel peptides described in this study, At1.1 and At1.2 (the analog with an L16I mutation), AtIA[des1Z], and AtIA[des18W], were synthesized using solid-phase Fmoc peptide chemistry with an AAPPTec Apex 396 automated peptide synthesizer (Louisville, KY, USA). ..

    Activity Assay:

    Article Title: Preparation, Biological Activities, and Potential Applications of Hen Egg-Derived Peptides: A Review
    Article Snippet: , Chemical synthesis , Egg white protein , AAPPTEC 396 Automated Peptide Synthesizer. The 9-Fluorenylmethoxycarbonyloxy (Fmoc)-protected amino acid synthesis method peptide (RVPSLM). , α-glucosidase inhibitory activity , IC 50 23.07 μmol/L , [ ] . .. , , Fmoc-protected amino acid synthesis method. AAPPTEC: Apex 396 automated peptide synthesizer. Peptide QIGLF. , ACE-inhibitory activity , IC 50 75 μmol/L , [ ] . .. , Fmoc solid-phase peptide conditions. AAPPTEC: Apex 396 peptide synthesizer. Peptide MIR. , Dipeptidyl peptidase IV-inhibitory activity , IC 50 24.97 ± 0.80 mmol/L , [ ] .



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